High-density lipoprotein - Wikipedia High-density lipoprotein - Wikipedia

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This means that adipocytes must have glucose to oxidize in order to store fatty acids in the form of TAGs. How do I know this? At the risk of repeating myself, the liver manufactures cholesterol and sends it out within VLDLs.

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Synthesis of LPL occurs within adipocytes and the striated muscle cells of the heart and skeletal muscle on rough ER. In addition, different apoE alleles have demonstrated activities.

The presence of apoA-IV in the hypothalamus, a site intimately involved in regulating energy homeostasis, suggests that the effects exerted on appetite by apoA-IV may be due to direct hypothalamic synthesis and secretion. In Synthesis of lipoprotein capillaries of adipose tissue, skeletal muscle, and the heart, the fatty acids of chylomicrons are removed from the triglycerides by the action of lipoprotein lipase LPLwhich is found on the surface of the endothelial cells of the capillaries.

Conversely, normal insulin responsiveness results in increased D5D and D6D activity as does a caloric restriction diet. The ELOVL6 encoded enzyme elongates saturated fatty acids with 12, 14, and 16 carbon atoms with highest activity towards palmitic acid C Most plaques, if left alone, do gradually reduce in size — a bit.

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There are two major forms PAF-AH, one that is cytosolic and one that is secreted and found in the plasma. Endothelial lipase is so-called because it is expressed exclusively by endothelial cells.

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The red T-lines indicate inhibition. There are leptin receptors in the gut and, therefore, leptin binding to these receptors could lead to direct effects on intestinal enterocytes.

Like fat oxidation, fat synthesis involves four primary enzymatic activities.

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LRP1 has been shown to bind more than 40 different ligands that include lipoproteins, extracellular matrix proteins, cytokines and growth factors, protease and protease inhibitor complexes, and viruses. It's almost impossible to know where to start without ranting.

Phospholipid Composition of Various Mammalian Membranes (% total phospholipid)

Does this really represent powerful enough evidence to warrant starting a four-year-old child on statins, and keeping them on for the rest of their life? As yet, the precise biochemical function s of the FADS3 gene in humans remains unclear.

The most commonly added alcohols serine, ethanolamine and choline also contain nitrogen that may be positively charged, whereas, glycerol and inositol do not.

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The significance of the numerous receptors on the surface of macrophages that specifically bind oxLDL is that the consequences are an enhanced intravascular inflammatory state.

The fatty acid portion of VLDLs is released to adipose tissue and muscle in the same way as for chylomicrons, through the action of lipoprotein lipase. So, pretty damned serious.

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Cretinism occurs in two forms, although there is considerable overlap.